Research Images as Art / Art Images as Research 2019/20

Honourable Mention

Honourable Mention

Miss Tahmina Aktar, Institute of Neurologys

A bouquet of hope for Charcot Marie Tooth Disease

Charcot Marie Tooth Disease (CMT) is an inherited neuromuscular disease characterised by muscle weakness and atrophy. Neuromuscular junctions (NMJs) are the site of contact between a motor neurone and the muscle. They are essential to permit the correct functioning and maintenance of skeletal muscle contraction. In CMT, NMJs are characterised by a weakened defective signal which correlates with disease severity and which has been identified as a potential therapeutic target for CMT. My image captures the two main components of NMJs: acetylcholine receptors in the post synaptic area ( in magenta) and their corresponding nerves and vesicles (in cyan) at the pre synaptic area.

Produced: Fluorescent microscopy

 


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