Runner-Up

Runner-Up

Mrs Larissa Mendes, Cancer Institute

“Chaos is order yet undeciphered”

Histological grading of tumours measure differentiation, i.e. how much a tumour resembles its tissue of origin. As a rule of thumb, the higher the grade, the lower the differentiation and the more clinically aggressive a tumour is. Here I applied a combination of digital filters to 3 different histological patterns of Prostate Cancer from lowest to highest grade highlighting how the different visual components get increasingly mixed up, looking more and more chaotic. Part of my research aims to show how subtle morphological variances within highly anarchic histologies can predict outcomes including different responses to available treatments and ultimately improving the management of patients affected by this disease. The title of this composition is a quote from Jose Saramago’s novel РThe Double.

Produced: confocal micrograph

 


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